Dionex AS50 Thermal Compartment Manual

The Dionex AS50 Thermal Compartment is a precision temperature-controlled module designed for chromatographic applications, providing stable thermal environments for analytical columns and samples. It features precise temperature control from 5°C to 80°C, rapid heating and cooling capabilities, compatibility with various Dionex systems, and advanced thermal management technology. Below are key sections for safety, features, installation, operation, maintenance, and troubleshooting.

1. Features at a Glance 2. Installation 3. First-Time Setup 4. Specifications 5. Controls and Settings 6. Connecting to Systems 7. Operation Procedures 8. Maintenance & Cleaning 9. Regulatory Information 10. Troubleshooting

Features at a Glance

Key components: Thermal compartment housing, temperature control unit, column mounting system, interface ports, and status indicators.

Feature	Description
Temperature Range	5°C to 80°C with ±0.1°C stability
Heating/Cooling Rate	Rapid thermal cycling capability
Column Capacity	Supports up to 2 analytical columns
Interface Ports	RS-232 and USB connectivity
Power Requirements	100-240V AC, 50/60Hz
Status Indicators	LED display for temperature and operation status
Safety Features	Over-temperature protection, door interlock
Compatibility	Dionex ICS-5000, ICS-3000 systems
Dimensions	Standard rack-mount configuration
Weight	Approximately 8.5 kg

Installation

Unpack and inspect contents. Install in appropriate system rack or bench space.

Position compartment: Ensure adequate ventilation space around unit.
Mount in system: Secure using provided mounting hardware in compatible Dionex system.
Connect power: Use provided power cable to appropriate outlet.
Connect to system: Use interface cables to connect to main chromatography system.
Install columns: Mount analytical columns according to application requirements.

WARNING! Ensure proper ventilation; do not block air vents. Use only specified power sources.

First-Time Setup

Power on compartment; initialize through system software.

Power connection: Connect to appropriate power source and turn on main switch.
System integration: Connect to Dionex chromatography system via interface cables.
Software configuration: Access thermal compartment settings through Chromeleon or equivalent software.
Temperature calibration: Perform initial temperature calibration if required.
Test operation: Run diagnostic test to verify proper functionality.

CAUTION! Allow compartment to reach room temperature before initial power-up.

Specifications

Temperature Range: 5°C to 80°C
Temperature Stability: ±0.1°C
Heating Rate: Up to 10°C per minute
Cooling Rate: Dependent on ambient conditions
Dimensions: Standard 19-inch rack mount
Weight: 8.5 kg
Power Requirements: 100-240V AC, 50/60Hz, 150W max
Communication: RS-232, USB 2.0
Operating Environment: 15°C to 35°C, 20-80% relative humidity
Column Compatibility: Standard 1/4" and 1/2" analytical columns

Controls and Settings

Access controls through system software interface. Front Panel: Power switch, status LEDs, temperature display.

Software Controls: Temperature setpoint, ramp rates, hold times, method programming.

Temperature Settings: Setpoint control, ramp programming, stability monitoring. Safety: Over-temperature protection, door safety interlock. Diagnostics: System status, error logging, performance monitoring.

Connecting to Systems

Interface with Dionex chromatography systems via standard communication ports.

Power off all equipment before making connections.
Connect communication cables: RS-232 or USB to main system controller.
Connect power cable to appropriate outlet.
Verify connections are secure and properly seated.
Power on system and initialize communication.

Tip: Use shielded cables for communication connections to minimize interference.

Operation Procedures

Standard operation for analytical applications.

Power on: Switch on main power and allow system to initialize.
Set temperature: Program desired temperature through software interface.
Load columns: Install analytical columns according to method requirements.
Start method: Initiate chromatographic method through system software.
Monitor operation: Observe temperature stability and system performance.
Shutdown: Follow proper shutdown procedure when analysis complete.

WARNING! Do not open compartment door during operation; allow to cool if necessary.

Maintenance & Cleaning

Regular maintenance ensures optimal performance and longevity.

Exterior cleaning: Use mild detergent and soft cloth for exterior surfaces.
Interior cleaning: Clean interior with isopropyl alcohol if contamination occurs.
Ventilation: Ensure air vents remain clear of dust and obstructions.
Inspection: Regular visual inspection for wear or damage.
Calibration: Periodic temperature calibration as recommended.

CAUTION! Disconnect power before cleaning. Use only approved cleaning agents.

Regulatory Information

CE Mark: Complies with European Union directives. FCC Part 15: Class A digital device; may cause interference in residential areas. RoHS compliant: Meets Restriction of Hazardous Substances requirements. For technical support, contact Dionex Technical Support or visit www.thermofisher.com/dionex.

Troubleshooting

Symptom	Possible Cause	Corrective Action
Temperature unstable	Ventilation blocked	Clear air vents; ensure proper airflow.
No power	Power connection	Check power cable; verify outlet function.
Communication error	Cable/port issue	Check cable connections; restart system.
Over-temperature error	Ambient conditions	Check room temperature; ensure ventilation.
Door interlock fault	Door sensor	Ensure door fully closed; check sensor alignment.

Reset: Power cycle unit; restart system software.

Service: Contact Dionex Technical Support; authorized service personnel only.