Dionex ASRS 300 Suppressor Manual

The Dionex ASRS 300 is an advanced electrolytically regenerated suppressor for ion chromatography systems, providing continuous chemical suppression to reduce background conductivity and enhance analyte detection. Features include automatic regeneration, chemical resistance, low noise operation, and compatibility with various IC systems. Below are key sections for safety, features, installation, operation, maintenance, and troubleshooting.

1. Features at a Glance 2. Installation 3. First-Time Setup 4. Specifications 5. Controls and Settings 6. Connecting to IC System 7. Operation Procedures 8. Maintenance & Cleaning 9. Regulatory Information 10. Troubleshooting

Features at a Glance

Key components: Suppressor module, electrical connectors, fluidic ports, regeneration system, pressure sensors.

Feature	Description
Electrolytic regeneration	Continuous chemical suppression without external regenerant
Chemical resistance	Compatible with common IC eluents and solvents
Low noise operation	Enhanced detection sensitivity
Automatic operation	Integrated with IC system software
Pressure monitoring	Built-in pressure sensors for system protection
Compact design	Space-efficient for modern IC systems
LED indicators	Status monitoring for operational states
Self-cleaning capability	Automated cleaning cycles
Temperature compensation	Stable performance across operating range
Digital interface	RS-232 or USB connectivity

Installation

Unpack and inspect contents. Ensure proper laboratory environment.

Mount suppressor: Secure in designated IC system location using mounting bracket.
Connect fluidic lines: Attach eluent inlet and outlet ports with appropriate tubing.
Electrical connection: Connect power and data cables to IC system controller.
Waste connection: Route suppressor waste line to proper disposal container.
System integration: Connect to IC system following manufacturer's guidelines.

WARNING! Handle with care to avoid damage to fluidic connections. Ensure all connections are secure before powering on.

First-Time Setup

Power on IC system; follow initialization procedure.

System recognition: Ensure IC software detects ASRS 300 suppressor.
Initial conditioning: Run recommended conditioning protocol with deionized water.
Pressure testing: Verify system holds pressure without leaks.
Performance verification: Run standard test mixture to confirm suppression efficiency.
Parameter configuration: Set operating parameters in IC software interface.

CAUTION! Use appropriate personal protective equipment during installation and setup.

Specifications

Model: ASRS 300 4mm
Suppression Capacity: >50 μeq/min
Maximum Pressure: 150 psi (10.3 bar)
Operating Temperature: 10°C to 40°C
Electrical Requirements: 24V DC, 1.5A
Fluidic Connections: 1/16" PEEK fittings
Dimensions: 150mm x 85mm x 45mm
Weight: 0.8 kg
Compatibility: Dionex ICS series and compatible IC systems
Warranty: 1 year limited warranty

Controls and Settings

Access control via IC system software interface. Hardware controls: Power switch, status LED.

Software Parameters: Suppression current, regeneration mode, cleaning cycles, pressure limits.

Operating Modes: AutoRegen, External Water, Recycle. Current Settings: 50-300 mA range. Pressure Monitoring: High/low pressure alarms. Maintenance Settings: Automated cleaning schedules, performance diagnostics.

Connecting to IC System

Fluidic: Eluent inlet/outlet ports. Electrical: Power and data connections.

Turn off IC system before making connections.
Connect eluent line from IC pump to suppressor inlet.
Connect suppressor outlet to detector cell.
Attach power cable to suppressor power supply.
Connect data cable to IC system controller.
Route waste line to appropriate container.

Tip: Use proper tubing and ensure all fittings are finger-tight to prevent leaks.

Operation Procedures

Standard operation with IC system software control.

Power on: Ensure IC system and suppressor are powered.
System prime: Prime fluidic lines to remove air bubbles.
Method selection: Choose appropriate IC method with suppressor settings.
Current setting: Set suppression current based on eluent composition.
Start analysis: Begin chromatographic run with suppressor active.
Monitor performance: Watch baseline conductivity and pressure readings.
Shutdown: Follow proper shutdown procedure including suppressor conditioning.

WARNING! Do not exceed maximum pressure ratings. Monitor system for leaks during operation.

Maintenance & Cleaning

Regular maintenance ensures optimal performance and longevity.

Daily: Check for leaks, verify pressure readings.
Weekly: Run cleaning protocol with recommended solutions.
Monthly: Performance verification with test standards.
As needed: Replace suppressor based on performance degradation.

Cleaning Solutions: 100mM HCl for cation removal, 100mM NaOH for organic removal.

CAUTION! Use appropriate chemical handling procedures. Flush thoroughly with DI water after cleaning.

Regulatory Information

CE Mark: Complies with European Union safety standards. RoHS Compliance: Meets Restriction of Hazardous Substances directive. FCC Part 15: Class A digital device. Copyright © 2024 Thermo Fisher Scientific. For technical support, contact Thermo Fisher Scientific or visit www.thermofisher.com.

Troubleshooting

Symptom	Possible Cause	Corrective Action
High background conductivity	Exhausted suppressor	Replace suppressor; check regeneration current
Pressure fluctuations	Blockage or air bubbles	Check for obstructions; prime system
No suppression current	Electrical connection	Verify power and data connections; check cables
Leaks at connections	Loose fittings	Tighten fittings; replace damaged tubing
Poor peak shape	Contamination	Run cleaning protocol; replace suppressor if needed

Reset: Power cycle suppressor; reinitialize in software.

Service: Contact Thermo Fisher Scientific technical support for assistance.